Below are the fixtures and results from the TotalEnergies CAF Confederation Cup of the 2024/2025 season of the second-leg matches of the second preliminary round. All times are in GMT Friday 20 September *Stade Malien Bamako 3-1 Paynesville Stade Malien Bamako advance 3-2 on aggregate *Zamalek 2-1 Police FC Zamalek advance 3-1 on aggregate *RSB Berkane 5-0 Dadjè Berkane advance 7-0 on aggregate Saturday 21 September *Sekhukhune United 1-2 Desportivo Lundavs Sul Desportivo Lundavs Sul advance 3-1 on aggregate *CS Constantine 1-0 Nsoatreman CS Constantine advance 3-0 on aggregate *CS Sfaxien 1-0 Rukinzo CS Sfaxien advance 2-0 on aggregate Sunday 22 September *13:00 Simba 3-1 Al Ahli Tripoli Simba advance 3-1 on aggregate *Dynamos 0-1 Orapa United 1-1 on aggregate, Orapa United advance 3-1 on penalties *Vita Club 1-1 Stellenbosch Stellenbosch advance 3-1 on aggregate *Saint Eloi Lupopo 1-2 Bravos do Maquis Bravos do Maquis advance 3-1 on aggregate *Otôho d'Oyo 2-1 Black Bulls Maputo 2- 2 on aggregate, Otoho d'Oyo advance on away goals rule *Enyimba 0-0 EF Ouagadougou 0-0 on aggregate, Enyimba advance 3-2 on penalties *Masry 3-2 Al Hilal 5-5 on aggregate, Masry advance on penalties *ASEC Mimosas 2-0 Kara ASEC advance 3-2 on aggregate *Jaraaf 3-0 Racing d'Abidjan Jaraaf advance 3-0 on aggregate *USM Alger 2-0 Stade Tunisien USM Alger advance 2-1 on aggregate Source: Confederation of African Football